ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
David T. George
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by George, D. T.
Right arrow Search for Related Content
PubMed
Right arrow Articles by George, D. T.
Related Collections
Right arrowRelated Article

Ann Thorac Surg 1996;61:645
© 1996 The Society of Thoracic Surgeons

Invited Commentary

Invited Commentary

David T. George, PhD

Division of Cardiothoracic Surgery Case Western Reserve University School of Medicine, B-27 10900 Euclid Ave Cleveland, OH 44106-4929

The first 20% of the full text of this article appears below.

See also page 640.

Kinoshita and colleagues present a case for atrophy of residual intact myocardium due to long-term unloading with a left ventricular assist device (LVAD). This group has accomplished some difficult studies in the past using coronary artery ligation to induce profound heart failure [1]. Unfortunately, their clinical correlation is limited in the present study because they studied normal hearts. Kinoshita and colleagues recognize this limitation, pointing out that ``myocardial atrophy in the intact ventricle after long-standing unloading ... may not directly indicate that atrophy also occurs in remaining viable myocardium in a clinical setting ...''.

This study underscores the disparate findings of experimental and clinical studies concerning myocardial atrophy after long-term unloading of the left ventricle. It is intuitive that chronic unloading could cause myocardial atrophy just as increased afterload causes myocardial hypertrophy. Intuition aside, observations . . . [Full Text of this Article]


Related Article

Influence of Prolonged Ventricular Assistance on Myocardial Histopathology in Intact Heart
Masayuki Kinoshita, Hisateru Takano, Shigeko Takaichi, Yoshiyuki Taenaka, and Takeshi Nakatani
Ann. Thorac. Surg. 1996 61: 640-645. [Abstract] [Full Text]





HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 1996 by The Society of Thoracic Surgeons.