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Ann Thorac Surg 1996;61:8-9
© 1996 The Society of Thoracic Surgeons


Editorials

Stratifying Patients Preoperatively for Transfusion Outcomes

Lawrence T. Goodnough, MD

Department of Medicine and Pathology, Washington University School of Medicine, Barnes Hospital, St. Louis, Missouri

The first 20% of the full text of this article appears below.

It has been estimated that 11% of the national red cell resource was used for transfusion support of patients undergoing coronary artery bypass grafting (CABG) in the United States in 1990 [1]. The magnitude of this need, along with the realization that blood safety was compromised by viral agents such as human immunodeficiency virus and hepatitis C virus, has led to studies that have served as descriptive analyses of transfusion outcomes in patients undergoing CABG. For example, determinants of blood use during myocardial revascularization have been identified to include such preoperative factors as female sex, age, preoperative hematocrit level, and preoperative red blood cell mass [2, 3]. Later, a multicenter study of transfusion outcomes in patients undergoing primary, elective CABG demonstrated a marked variability in the transfusion of red cells, plasma, and platelets among institutions, despite apparent homogeneity in these preoperative patient factors that were known to determine blood use [4]. The variability in transfusion outcomes independent of patient factors has been attributed to differences in transfusion triggers, surgical technique, blood conservation strategies, inappropriate transfusions, or a combination of these. What has been lacking, until now, is a validated scoring system that can assess the relevant patient factors, stratify patients at risk for transfusion, and predict . . . [Full Text of this Article]


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Ann. Thorac. Surg. 1996 61: 27-32. [Abstract] [Full Text]



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