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Ann Thorac Surg 1995;60:962-963
© 1995 The Society of Thoracic Surgeons

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Invited Commentary

Invited Commentary

University Hospital and the Robarts Research Institute PO Box 5339 London, Ontario N6A 5A5 Canada

The first 20% of the full text of this article appears below.

See also page 958.

The practice of lung transplantation has been constrained by a marked shortage of donor organs. Studies have revealed that only a small percentage of potential donors have lungs that are suitable for transplantation because of aspiration pneumonitis, infection, neurogenic pulmonary edema, iatrogenic overhydration, lung contusion, and less commonly preexisting pulmonary disease in the donor [1–3]. Even in cases of ``optimal'' donor lungs, graft preservation times are limited to 6 to 8 hours and pulmonary dysfunction after transplantation is not uncommon [4, 5]. New strategies to improve the preservation of lung grafts are thus essential. Whereas . . . [Full Text of this Article]

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