Ann Thorac Surg 1995;60:244
© 1995 The Society of Thoracic Surgeons
Discussion
Discussion
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See also page 239.
DR THOMAS M. EGAN (Chapel Hill, NC): What do you think the cardiac toxicity would be in vivo, and have you looked at that in any surviving rats that you have perfused?
DR PORT: There is evidence that glutathione may provide cardioprotection from agents such as doxorubicin. Therefore, there has been considerable hesitancy in using BSO, an inhibitor of glutathione, with systemic doxorubicin therapy. We have demonstrated in our model of isolated lung perfusion . . . [Full Text of this Article]
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Copyright © 1995 by The Society of Thoracic Surgeons.