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Ann Thorac Surg 2009;88:1921-1922. doi:10.1016/j.athoracsur.2009.08.029
© 2009 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Ian M.C. Dixon, PhD

ICVS, Department of Physiology, University of Manitoba, Room 3038, SBGH Research Centre, 351 Tache Ave, Winnipeg, MB, R2H 2A6 Canada

(Email: idixon@sbrc.ca).

The first 20% of the full text of this article appears below.

Oliver Wendell Holmes, the American physician and humorist offered the following quote: "The great thing in the world is not so much where we stand, as in what direction we are moving." This is certainly true of the field of extracellular matrix biology, especially in the context of heart disease. Despite the pioneering work of Weber, Borg, Caulfield, and others, the role of the cardiac matrix was somewhat ignored as a player in the pathogenesis of heart failure until the past decade. This . . . [Full Text of this Article]


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Ann. Thorac. Surg. 2009 88: 1916-1921. [Abstract] [Full Text] [PDF]





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