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Department of Anesthesiology & Critical Care Medicine, The Johns Hopkins Hospital, 600 N Wolfe St, Tower 711, Baltimore, MD 21287
(Email: chogue2@jhmi.edu).
| The first 20% of the full text of this article appears below. |
Assessing neuropsychological testing performance has been widely used as a means for detecting subtle brain injury from cardiac surgery. As the demographics of patients change to include more elderly patients and those with hypertension, diabetes, and other conditions, controlling for the effects of cerebral vascular disease on perioperative cognitive test results becomes important. In a seminal report, Selnes and colleagues [1], for example, followed a cohort of patients undergoing coronary artery bypass surgery (CABG) surgery with cardiopulmonary bypass and a group of patients with documented coronary artery disease undergoing medical management for 6 years. These investigators found that late cognitive decline after CABG surgery was
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