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Ann Thorac Surg 2009;88:535-536. doi:10.1016/j.athoracsur.2009.04.031
© 2009 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Vincent Chan, MD, Marc Ruel, MD, MPH

Departments of Surgery, Epidemiology, and Cellular and Molecular Medicine, University of Ottawa Heart Institute, 40 Ruskin St, Suite 3403, Ottawa, Ontario, Canada K1Y 4W7

(Email: mruel@ottawaheart.ca).

The first 20% of the full text of this article appears below.

Cardiopulmonary bypass (CPB) has been germane to the development of cardiac surgery. Although its use is often necessary, CPB is associated with the development of a well-described systemic inflammatory response. Benedetto and colleagues [1] examined the hypothesis that the Medtronic Resting Heart System mini-CPB circuit (Medtronic Inc, Minneapolis, MN) reduces acute kidney injury (AKI) by mitigating systemic inflammatory pathways by minimization of the blood-artificial surface interface.

In an observational study of 705 coronary artery bypass grafting (CABG) patients, Benedetto and colleagues [1] . . . [Full Text of this Article]


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Miniaturized Cardiopulmonary Bypass and Acute Kidney Injury in Coronary Artery Bypass Graft Surgery
Umberto Benedetto, Remo Luciani, Massimo Goracci, Fabio Capuano, Simone Refice, Emiliano Angeloni, Antonino Roscitano, and Riccardo Sinatra
Ann. Thorac. Surg. 2009 88: 529-535. [Abstract] [Full Text] [PDF]





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