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Ann Thorac Surg 2009;87:1213. doi:10.1016/j.athoracsur.2009.02.051
© 2009 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Jakob Vinten-Johansen, PhD

Cardiothoracic Surgery, Emory University, Cardiothoracic Research Laboratory, Carlyle Fraser Heart Center, 550 Peachtree St, NE, Atlanta, GA 30308-2225

(Email: jvinten@emory.edu).

The first 20% of the full text of this article appears below.

Depolarizing the heart with hyperkalemic cardioplegia solutions arrests the heart but is associated with an on-going, albeit lowered, metabolic demand that requires either hypothermia or intermittent/continuous delivery to attenuate the consequences of this ongoing demand (ie, ischemia). However, simplicity, visibility, economy, and avoiding the consequences of systemic hyperkalemia would make a single delivery of hypothermic cardioplegia desirable, especially during aortic arch repairs and other complex procedures that require long arrest times.

Fannelop and colleagues [1] have compared physiologic outcomes of a single infusion of Custodiol HTK (Odyssey Pharmaceuticals Inc, East Hanover, NJ) crystalloid cardioplegia solution with a multidose strategy . . . [Full Text of this Article]


Related Article

Multidose Cold Oxygenated Blood Is Superior to a Single Dose of Bretschneider HTK-Cardioplegia in the Pig
Tord Fannelop, Geir Olav Dahle, Pirjo-Riitta Salminen, Christian Arvei Moen, Knut Matre, Arve Mongstad, Finn Eliassen, Leidulf Segadal, and Ketil Grong
Ann. Thorac. Surg. 2009 87: 1205-1213. [Abstract] [Full Text] [PDF]





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Copyright © 2009 by The Society of Thoracic Surgeons.