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Department of Cardiopulmonary Bypass, Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Beijing Institute of Heart, Lung, & Vascular Diseases, Capital Medical University, No. 2, Anzhen Rd, Anzhen Li, Anding Menwai, Beijing, 100029 China
(Email: dr.yiluo@gmail.com).
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To the Editor:
We read with great interest the article by Siepe and colleagues [1]. In this particular animal research, to avoid ischemia of the lungs during cardiopulmonary bypass (CPB), the authors used active pulmonary perfusion and compared the effects of two different perfusion modes (pulsatile vs nonpulsatile perfusion) on pulmonary inflammatory response and apoptosis in the lungs. They concluded that active pulsatile pulmonary perfusion reduces the inflammatory response and apoptosis in the lungs during CPB. Siepe and colleagues should be congratulated on their excellent experimental design and results. We believe that their original idea on this topic is a good attempt to use active pulsatile perfusion
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Ann. Thorac. Surg. 2009 87: 989.
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B. Ji, X. Wang, J. Liu, and C. Long Does the pulse play an important role during pulsatile pulmonary perfusion Eur J Cardiothorac Surg, December 1, 2011; 40(6): 1552 - 1553. [Full Text] [PDF] |
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M. Siepe, C. Schlensak, and U. Goebel Reply Ann. Thorac. Surg., March 1, 2009; 87(3): 989 - 989. [Full Text] [PDF] |
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