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a Lung Cancer and Thoracic Oncology Program, City of Hope National Medical Center, 1500 E. Duarte Rd, Warsaw MOB, Duarte, CA 91010-3000
b Medical Data Research Center, Providence Health System, 44785 NW Elk Mountain Rd, Banks, OR 97106
(Email: kkernstine@coh.org).
| The first 20% of the full text of this article appears below. |
In the 1990s, fluorodeoxyglucose positron emission tomography (FDG-PET) was introduced as a part of the evaluation of suspicious solitary pulmonary nodules, and visual assessment and the maximum standard uptake value (SUVmax) pixel in the region of interest have been used to estimate the likelihood of malignancy [1, 2]. Most studies have concentrated on larger lesions of 3 cm or more [3]. FDG-PET is unlikely to be as accurate for the smaller lesions. So, the question asked by Ohba and colleagues [4]—can the accuracy of FDG-PET be improved in evaluating malignancy in lesions less than 3 cm?—is certainly relevant.
Others have attempted to improve the accuracy of PET by manipulating the emission results [2, 5]. Ohba and colleagues,
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