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Department of Cardiac Surgery, Zhongshan Hospital, Fudan University, 180 Fenling Rd, Shanghai, 200032 China
(Email: zhao.qiang@zs-hospital.sh.cn).
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This article by Hamamoto and colleagues [1] reports the effect of cell dosage of allogenic mesenchymal precursor cell therapy on the post-myocardial infarction left ventricular remodeling in a sheep transmural myocardial infarct model.
Using allogeneic stem cells and off-the shelf availability is the ultimate clinical destination of cell therapy for ischemic heart disease. Cell banks can be built up with in vitro culture of stem cells donated from young and healthy volunteers. This technique provides vast amounts of myocardial cells and enables transplanting cells into any patient
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Ann. Thorac. Surg. 2009 87: 794-801.
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