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Ann Thorac Surg 2009;87:473-474. doi:10.1016/j.athoracsur.2008.10.036
© 2009 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Annie Laurie W. Shroyer, PhDa, Gary K. Grunwald, PhDb

a Research and Development Office, Northport Veterans Affairs Medical Center, 79 Middleville Rd (151), Northport, NY 11768
b Division of Cardiac Research, Department of Veterans Affairs and, Department of Biostatistics and Informatics, University of Colorado Denver, Box B-119, 4200 E 9th Ave, Denver, CO 80262

(Email: annie.shroyer@va.gov; gary.grunwald@ucdenver.edu).

The first 20% of the full text of this article appears below.

In this timely and clinically relevant article, MacKenzie and colleagues [1] have developed statistical models for predicting survival up to 8 years after coronary artery bypass graft (CABG) or percutaneous coronary intervention (PCI) based on 10 plus years (> 35,000 records) from the Northern New England Cardiovascular Disease Study Group (NNECDSG) database. They have quantified the major risk associations and made the resulting models and survival predictions available to investigators and clinicians.

MacKenzie and colleagues [1] elegantly applied sophisticated statistical methods to meet major analytical challenges, including time to event outcomes (Cox survival models), nonproportional hazards over long time periods (clever use of time partitions), nonlinearity of risk associations (splines), different associations of risk variables with postintervention survival at . . . [Full Text of this Article]


Related Article

Prediction of Survival After Coronary Revascularization: Modeling Short-Term, Mid-Term, and Long-Term Survival
Todd A. MacKenzie, David J. Malenka, Elaine M. Olmstead, Winthrop D. Piper, Craig Langner, Cathy S. Ross, Gerald T. O'Connor Northern New England Cardiovascular Disease Study Group
Ann. Thorac. Surg. 2009 87: 463-472. [Abstract] [Full Text] [PDF]





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Copyright © 2009 by The Society of Thoracic Surgeons.