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Ann Thorac Surg 2009;87:137-138. doi:10.1016/j.athoracsur.2008.11.002
© 2009 The Society of Thoracic Surgeons
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Original Articles: Adult Cardiac

Invited Commentary

Robert Poston, MD

Division of Cardiac Surgery, Boston University, 88 E Newton, Robinson 402, Boston, MA 02118

(Email: robert.poston@bmc.org).

The first 20% of the full text of this article appears below.

Because hemostasis and thrombosis share many of the same mechanisms, conventional wisdom dictates that the bleeding patient is at less risk for thromboembolism. However, ventricular assist device (VAD) recipients are often plagued by both of these events simultaneously [1]. Unfortunately, the tools to investigate this paradox of bleeding patients with clotted pumps are lacking because clinically available assays of coagulation are mostly ineffective at predicting bleeding or thromboembolism during VAD support.

To address this knowledge deficit, Steinlechner and colleagues [2] assessed coagulation and platelet function in 12 VAD patients, focusing their attention on von Willebrand factor (vWF), a . . . [Full Text of this Article]


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Ann. Thorac. Surg. 2009 87: 131-137. [Abstract] [Full Text] [PDF]





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