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Original Articles: Pediatric Cardiac

Invited Commentary

Mayo Clinic, 200 First Street SW, Rochester, MN 55905

(Email: oliver.william@mayo.edu).

The first 20% of the full text of this article appears below.

With the demand for pediatric donor hearts continuing to exceed a decreasing supply, the bridge to transplantation plays an ever important role in the survival of pediatric patients with intractable myocardial failure. Since the first bridge to transplant occurred in 1989 in a 9-year-old that underwent successful orthotopic heart transplantation after 12 hours of support on a Biomedicus centrifugal pump (Medtronic, Minneapolis, MN), extracorporeal membrane oxygenation or ventricular assist device (VAD) with centrifugal flow were the mainstay of circulatory support to reach transplantation. However, bridge to transplantation with extracorporeal membrane oxygenation is limited to approximately 2 weeks to attain acceptable survival and hospital discharge. It is not unusual to wait 2 to 3 months listed as . . . [Full Text of this Article]

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