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Original Articles: Adult Cardiac

Invited Commentary

Division of Cardiothoracic Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China

(Email: swan@cuhk.edu.hk).

The first 20% of the full text of this article appears below.

Aiming to limit blood loss, the recycling of cardiotomy blood shed during open-heart operations with the use of cardiopulmonary bypass (CPB) has been a routine, worldwide practice for the past 5 decades. Nonetheless, the majority of cardiac surgeons recognize that the pericardial blood shed not only contains a mixture of debris, but is also a rich source of activated tissue factors, markers of clotting and fibrinolysis, and pro-inflammatory mediators. Therefore, it has generally been the belief that the intraoperative application of a cell saver could be beneficial in reducing neurologic impairment after CPB (ie, limiting cerebral microemboli) and improving blood conservation through autologous . . . [Full Text of this Article]

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