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Ann Thorac Surg 2008;86:1129-1130. doi:10.1016/j.athoracsur.2008.06.081
© 2008 The Society of Thoracic Surgeons

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Federico Venuta
Marco Anile
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Original Articles: General Thoracic

Invited Commentary

Federico Venuta, MD, Marco Anile, MD

University of Rome "La Sapienza", Department of Thoracic Surgery, Policlinico Umberto I, V.le del Policlinico, Rome, 00100 Italy

(Email: federico.venuta@uniroma1.it).

The first 20% of the full text of this article appears below.

A number of different techniques for lung preservation have been tested in experimental models; many of them were successfully transferred to the clinical practice. However, none of these techniques is ideal because the early function of the transplanted lungs may still be deranged by primary graft dysfunction. High-volume antegrade pulmonary artery flushing with extracellular solutions is currently the most widely used method of lung preservation. However, it still presents some drawbacks (ie, pulmonary arterial vasoconstriction requires bolus injection of prostaglandin E; the bronchial circulation is not perfused; clots and fat emboli may jeopardize the uniformity of flushing and graft reperfusion). Retrograde pneumoplegia delivered through the pulmonary veins may help to eliminate the residual blood, clots, and fat emboli; it is uniformly distributed and also flushes the bronchial circulation [1–5]. This technique has . . . [Full Text of this Article]


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Ann. Thorac. Surg. 2008 86: 1123-1129. [Abstract] [Full Text] [PDF]






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