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a Department of Cardiovascular Anesthesia and Intensive Care, San Raffaele Hospital, Via Olgettina 60, Milan, 20132 Italy
b Institut für Immunologie und Transfusionsmedizin, Abteilung Transfusionsmedizin, Ernst-Moritz-Arndt-Universität Greifswald, Sauerbruchstrasse, 17475 Greifswald
(Email: pappalardo.federico@hsr.it; greinach@uni-greifswald.de; sixten.selleng@uni-greifswald.de).
| The first 20% of the full text of this article appears below. |
To the Editor:
The article by Kerendi and colleagues [1] draws attention to post-cardiac surgery patients who present with thrombocytopenia and who also test positive for anti-Platelet Factor4/heparin antibodies. The authors used a commercially available enzyme-immunoassay (EIA) and found patients testing positive in this assay have an enhanced risk for thromboembolic complications, renal failure, and mortality as compared with antibody negative patients.
However, the study needs some comments, addressing the diagnosis of heparin-induced thrombocytopenia (HIT).
Related Article
Ann. Thorac. Surg. 2008 86: 1055.
This article has been cited by other articles:
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F. Kerendi, V. H. Thourani, J. D. Puskas, R. A. Guyton, and O. M. Lattouf Reply Ann. Thorac. Surg., September 1, 2008; 86(3): 1055 - 1055. [Full Text] [PDF] |
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