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Ann Thorac Surg 2008;86:375. doi:10.1016/j.athoracsur.2008.05.071
© 2008 The Society of Thoracic Surgeons
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Original Articles: General Thoracic

Invited Commentary

Lorenzo Spaggiari, MD, PhD

University of Milan, Milan, Department of Thoracic Surgery, European Institute of Oncology, Via Ripamonti 435, Milan, 20141 Italy

(Email: lorenzo.spaggiari@ieo.it).

The first 20% of the full text of this article appears below.

The article by Farjah and colleagues [1] is very interesting, and two aspects are relevant; on one hand, only 9% of patients affected by T4 nonsmall cell lung cancer (NSCLC) are eligible for lung resection; on the other, survival of a carefully selected group of patients may be very promising (5 yrs > 40%).

Patients affected by T4 NSCLC present a heterogeneous disease that is often associated with bulky lympho-nodal involvement; concurrent or sequential chemoradiotherapy represents the gold standard treatment, but 5-year survival is less than 10%.

"T4 multiple nodular" disease is a different oncological entity that does not require complex surgical procedures and that has a different oncological impact from "T4 mediastinal" disease. This group of T4 NSCLC (multiple . . . [Full Text of this Article]


Related Article

Trends in the Operative Management and Outcomes of T4 Lung Cancer
Farhood Farjah, Douglas E. Wood, Thomas K. Varghese, Jr, Rebecca Gaston Symons, and David R. Flum
Ann. Thorac. Surg. 2008 86: 368-374. [Abstract] [Full Text] [PDF]



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L. Spaggiari
Invited Commentary
Ann. Thorac. Surg., August 1, 2009; 88(2): 397 - 398.
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