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Hopital Europeen Georges Pompidou, Service de Chirurgie Thoracique, 20-40 rue Leblanc, Paris Cedex 15 75908, France
(Email: marc.riquet@hop.egp.ap-hop-paris.fr).
| The first 20% of the full text of this article appears below. |
To the Editor:
When we first reviewed factors determining overall survival of resected N2 nonsmall lung cancers (NSCLC) [1], we observed that the presence of a small metastasis in a mediastinal lymph node had the same clinical significance as that of a whole chain of tumor-bearing lymph nodes with extracapsular invasion.
In recent years, minimal N2 disease is emerging as a criterion of better prognosis for NSCLC patients with mediastinal lymph node involvement, and this understanding adds validity to the statement that primary surgical resection of more extensive N2 disease ("bulky
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