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Ann Thorac Surg 2008;85:2163-2164. doi:10.1016/j.athoracsur.2008.02.066
© 2008 The Society of Thoracic Surgeons
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Correspondence

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Takeyoshi Ota, MD, PhDa, Yutaka Okita, MD, PhDa, Yoshiki Sawa, MD, PhDb

a Department of Cardiovascular Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan
b Department of Surgery (E1), Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan

(Email: toota-cvs@umin.ac.jp; sawa@surg1.med.osaka-u.ac.jp).

The first 20% of the full text of this article appears below.

To the Editor:

We appreciate the comments by Drs Dohmen and Konertz [1] on our article [2] and for giving us an opportunity to describe further the explanation of our study.

Gamma irradiation played an important role in our decellularization process. The original purpose for use of gamma irradiation was to remove the cell components from the porcine aortic valves in conjunction with polyethylene glycol (PEG). Because the radiation effect can reach the entire tissue evenly, it contributed to complete decellularization of such porcine aortic valves that had . . . [Full Text of this Article]


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Decellularization of Xenogenic Biologic Tissue
Pascal Maria Dohmen and Wolfgang Konertz
Ann. Thorac. Surg. 2008 85: 2163. [Extract] [Full Text] [PDF]





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