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Ann Thorac Surg 2007;83:1803-1804
© 2007 The Society of Thoracic Surgeons

Original Articles: Cardiovascular

Invited commentary

Joanne Guay, MD

Department of Anesthesiology, Maisonneuve-Rosemont Hospital, 5415 L’Assomption Blvd, Montreal, QC, H1T 2M4 Canada

(Email: joanne.guay@umontreal.ca).

The first 20% of the full text of this article appears below.

Odegard and colleagues [1] are reporting decreased blood levels of various procoagulant and anticoagulant factors in children with two-ventricle congenital heart disease (CHD) under 4 years of age. The clinical implications of these findings are unclear. First, measuring the quantity of factors does not tell us how the system reacts globally. Apart from factor VIII, all coagulation factors are decreased at birth and an altered platelet function during the first years of life has also been shown [2]. Yet when the coagulation of infants is evaluated with a thromboelastograph, a relative hypercoagulable state is found [. . . [Full Text of this Article]


Related Article

Evaluation of the Coagulation System in Children with Two-Ventricle Congenital Heart Disease
Kirsten C. Odegard, David Zurakowski, Stephan Hornykewycz, James A. DiNardo, Robert A. Castro, Ellis J. Neufeld, and Peter C. Laussen
Ann. Thorac. Surg. 2007 83: 1797-1803. [Abstract] [Full Text] [PDF]





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