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Ann Thorac Surg 2007;83:1499-1500
© 2007 The Society of Thoracic Surgeons
Stem Cell Biology, Keck Graduate Institute, 535 Watson Dr, Claremont, CA 91711
(Email: ytang@kgi.edu; ian_phillips@kgi.edu).
| The first 20% of the full text of this article appears below. |
Heart failure due to acute myocardial infarction is a growing worldwide problem [1]. Cellular therapy with stem cells is a promising new approach for reversing left ventricular remodeling in ischemic heart disease. Regenerative medicine in cardiology is a new field based on the possibility of replacing lost cardiac cells and improving the function of injured hearts by cell transplantation. Adult cardiac tissue has limited regenerative capacity, although resident cardiac stem cells were recently discovered in the adult heart [2, 3]. However, the resident cardiac stem cells are in such low numbers, even though they can self-renew and regenerate the myocardium, myocardial damage is
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