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Ann Thorac Surg 2006;82:1649
© 2006 The Society of Thoracic Surgeons

Original Articles: Cardiovascular

Invited commentary

Igor Knez, MD, Gerfried Zobel, MD, Bruno Rigler, MD

Department of Surgery, University Hospital, Klin Abteilung fur Herzchirurgie, Med Univklinikum Graz, LKH, Auenbruggerplatz 29, Graz, 8036 Austria

(Email: bruno.rigler@meduni-graz.at).

The first 20% of the full text of this article appears below.

Isoenzyme cardiac troponin T (cTnT) is one component of a complex of three separate proteins that, together with tropomyosin, confers calcium sensitivity to the process of actin-myosin cross-bridge formation in the myocardial cell. Found exclusively in the myocardium, it is a potent inhibitor of these interactions and is a more sensitive and specific index of myocardial cell damage than creatine kinase-MB (CK-MB) fraction, CK-MB mass, and myoglobin level. Therefore, cTnT has emerged as a strong predictive variable of complications and clinical outcome after cardiac surgery.

Mildh and colleagues [1] report a series of 1001 consecutive pediatric patients operated on . . . [Full Text of this Article]


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Cardiac Troponin T Levels for Risk Stratification in Pediatric Open Heart Surgery
Leena H. Mildh, Ville Pettilä, Heikki I. Sairanen, and Paula H. Rautiainen
Ann. Thorac. Surg. 2006 82: 1643-1648. [Abstract] [Full Text] [PDF]





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