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Ann Thorac Surg 2006;82:1050-1051
© 2006 The Society of Thoracic Surgeons

Original article: General thoracic

Invited commentary

Niels P. van der Kaaij, MS, Ad J.J.C. Bogers, MD, PhD

Department of Cardiothoracic Surgery, Room Ee 173, Erasmus MC Rotterdam, Dr. Molewaterplein 50, Rotterdam, 3015 GE The Netherlands

(Email: npvdkaaij@gmail.com; a.j.j.c.bogers@erasmusmc.nl).

The first 20% of the full text of this article appears below.

The outcome after human lung transplantation remains limited, mainly due to development of the bronchiolitis obliterans syndrome (BOS). Development of BOS may be considered as a multiple injury hit model, in which all lung injury-causing factors (eg, ischemia-reperfusion injury, pneumonia, rejection, donor ventilation, and cytomegalovirus [CMV]) seem to have a (major or minor) role in BOS development. All these factors may interplay in BOS initiation and progression. However, pathological pathways by which (acute) lung injury factors may contribute to and interplay in BOS development and progression are mostly unclear.

The hypothesis of the experimental study by Kuo and colleagues [1. . . [Full Text of this Article]


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Respiratory Viral Infection in Obliterative Airway Disease After Orthotopic Tracheal Transplantation
Elbert Kuo, Ankit Bharat, Trudie Goers, Will Chapman, Le Yan, Tyler Street, Wei Lu, Michael Walter, Alexander Patterson, and Thalachallour Mohanakumar
Ann. Thorac. Surg. 2006 82: 1043-1050. [Abstract] [Full Text] [PDF]





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