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Ann Thorac Surg 2006;82:478-479
© 2006 The Society of Thoracic Surgeons

Original Articles: General Thoracic

Invited commentary

Thomas K. Varghese, Jr, MD

Section of Thoracic Surgery, University of Michigan, 2120 Taubman Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109

(Email: vargthom@umich.edu).

The first 20% of the full text of this article appears below.

Ischemia–reperfusion lung injury resulting in pulmonary dysfunction is a major source of morbidity and mortality after cardiac surgery and lung transplantation. Transbronchial biopsies performed after lung transplantation demonstrate histologic features of diffuse alveolar damage in more than 30% of patients [1]. This is associated with severe graft dysfunction in about 20% of recipients [2], and is the most common cause of early mortality after lung transplantation [3–5]. Postoperative lung dysfunction after cardiopulmonary bypass . . . [Full Text of this Article]






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