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Ashish S. Shah
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Ann Thorac Surg 2006;82:471
© 2006 The Society of Thoracic Surgeons

Original Articles: General Thoracic

Invited commentary

Ashish S. Shah, MD, John V. Conte, MD

Division of Cardiac Surgery, Johns Hopkins Medical Institutions, Blalock 618, 600 N Wolfe St, Baltimore, MD 21287

(Email: ashah@duke.edu; jconte@csurg.jhmi.jhu.edu).

The first 20% of the full text of this article appears below.

Donor organ manipulation on the molecular level has been an intriguing, exciting, and elusive proposition. As we learn more about donor organ function and dysfunction, it is clear that modulating receptors systems and inflammatory mediators may allow for improved allograft function. A variety of approaches are available, including gene transfer strategies, transgenic technology, and pharmacologic interventions. Nonetheless, very little from this fertile area of research has found its way into clinical lung transplantation to . . . [Full Text of this Article]






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Copyright © 2006 by The Society of Thoracic Surgeons.