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Ann Thorac Surg 2005;80:2234
© 2005 The Society of Thoracic Surgeons
Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA02215
(Email: jfeng@caregroup.harvard.edu; fsellke@caregroup.harvard.edu).
| The first 20% of the full text of this article appears below. |
Apoptosis or program cell death has been previously reported to occur during cardioplegic arrest and cardiopulmonary bypass (CPB), suggesting that apoptosis may, at least in part, contribute to myocardial stunning. Vähäsilta and colleagues [1] confirmed these previous findings in their in-vivo pig model and further tested the hypothesis that differences from retrograde and antegrade cardioplegia might translate into differences in appearance of apoptosis. In this interesting and important study, the authors found that retrograde cardioplegia induced higher amount of apoptosis cardiomyocyte death
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