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Ann Thorac Surg 2005;79:2201-2202
© 2005 The Society of Thoracic Surgeons

Correspondence

Adverse Effects of Local or Systemic Application of Rapamycin for the Prevention of Neointimal Hyperplasia

Beat H. Walpoth, MD, FAHA

Department of Surgery, University Hospital of Geneva, Geneva, CH 1211 Switzerland

(E-mail: beat.walpoth@hcuge.ch).

The first 20% of the full text of this article appears below.

To the Editor:

Schachner and colleagues [1] have shown in an elegant experimental study that rapamycin could inhibit the development of neointimal hyperplasia in vein grafts. This was done in a mouse autologous graft transplantation model (vein to artery), with and without a peri-paravascular application of rapamycin. Significant reduction of neointimal hyperplasia was observed in the . . . [Full Text of this Article]


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Thomas Schachner, Guenther Laufer, and Johannes Bonatti
Ann. Thorac. Surg. 2005 79: 2202. [Extract] [Full Text] [PDF]





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