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Ann Thorac Surg 2005;79:1337
© 2005 The Society of Thoracic Surgeons
Department of Physiology, University of Manitoba, Room 3038, SBGH Research Centre, 351 Tache Avenue, Winnipeg, MB R2H 2A6, Canada idixon@sbrc.cajraizman@sbrc.ca
| The first 20% of the full text of this article appears below. |
The dogma with respect to apoptosis and the biological fate of cardiac myocytes implicates the eventual death of those cells. Graded, suspended, or reversible apoptosis is a relatively unexplored entity in the setting of heart failure or cardiomyopathy. If cells that are expressing apoptotic genes (eg, caspase-3) could be "rescued" or recruited back into the functional myocardium using selective gene therapy emphasizing expression of genes
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