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Ann Thorac Surg 2005;79:1337
© 2005 The Society of Thoracic Surgeons


Original articles: Cardiovascular

INVITED COMMENTARY

Ian M.C. Dixon, PhD, Josh E. Raizman, BSc

Department of Physiology, University of Manitoba, Room 3038, SBGH Research Centre, 351 Tache Avenue, Winnipeg, MB R2H 2A6, Canada idixon@sbrc.cajraizman@sbrc.ca

The first 20% of the full text of this article appears below.

The dogma with respect to apoptosis and the biological fate of cardiac myocytes implicates the eventual death of those cells. Graded, suspended, or reversible apoptosis is a relatively unexplored entity in the setting of heart failure or cardiomyopathy. If cells that are expressing apoptotic genes (eg, caspase-3) could be "rescued" or recruited back into the functional myocardium using selective gene therapy emphasizing expression of genes . . . [Full Text of this Article]







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