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Ann Thorac Surg 2004;78:1884-1885
© 2004 The Society of Thoracic Surgeons

Correspondence

Pitfalls in the Measurement of Serum VEGF in Children With Congenital Heart Disease

Elisa Arena, MD

Di.S.C.A.T.University of GenoaLargo R. Benzi 816132 Genoa, Italy

Simone Ferrero, MD

Department of Obstetrics and Gynaecology, San Martino Hospital, University of Genoa, Largo R. Benzi 1, 16132 Genoa, Italy

elisaarena@hotmail.com
simone.ferrero@fastwebnet.it

The first 20% of the full text of this article appears below.

To the Editor:

We read the article by Ootaki and colleagues [1] with interest. We bring to your attention some methodological concerns that might have caused relevant bias in the conclusion. The concentrations of vascular endothelial growth factor (VEGF) were measured in serum samples, but there has been no validation of serum VEGF as an indicator of the extracellular circulating VEGF levels at the time of sampling. Vascular endothelial growth factor is . . . [Full Text of this Article]






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