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Ann Thorac Surg 2004;78:1562-1563
© 2004 The Society of Thoracic Surgeons

INVITED COMMENTARY

Diederik van Dijk, MD

University Medical Center Utrecht, Department of Anesthesiology Heidelberglaan 100, Utrecht, The Netherlands

ddijk@azu.nl

The first 20% of the full text of this article appears below.

Several studies have reported an association between aortic arteriosclerosis and the number of cerebral microemboli, detected by transcranial Doppler. The authors' hypothesis, that aortic disease not only predicts stroke but also neurocognitive dysfunction (NCD), is therefore very reasonable. They carried out a study in a substantial sample of 162 patients and measured cognitive performance at relevant time points. Yet, this study failed to establish such an association.

Retrospective studies may be carried out without a protocol and a clear analytical plan, designed before exploration of . . . [Full Text of this Article]






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