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Ann Thorac Surg 2004;78:969
© 2004 The Society of Thoracic Surgeons

Invited commentary

Robert Lasley, PhD

Department of Surgery, University of Kentucky College of Medicine, Room MN 276, Chandler Medical Center, 800 Rose St, Lexington, KY 40536–0298, USA

rlasley@uky.edu

The first 20% of the full text of this article appears below.

The study by Halkos and colleagues addressed the hypothesis that the combination of ischemic preconditioning and ischemic postconditioning exerts greater cardioprotection than either agent alone. This is an intriguing question from both a basic science standpoint and in terms of clinical relevance. Ischemic preconditioning has been shown to reduce numerous metabolic and ionic perturbations that occur during prolonged ischemia. Thus ischemic preconditioning appears to delay the onset of irreversible ischemic injury. Ischemic postconditioning, . . . [Full Text of this Article]


Related Article

Myocardial protection with postconditioning is not enhanced by ischemic preconditioning
Michael E. Halkos, Faraz Kerendi, Joel S. Corvera, Ning-Ping Wang, Hajime Kin, Christopher S. Payne, He-Ying Sun, Robert A. Guyton, Jakob Vinten-Johansen, and Zhi-Qing Zhao
Ann. Thorac. Surg. 2004 78: 961-969. [Abstract] [Full Text] [PDF]





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