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Ann Thorac Surg 2004;78:1009-1010
© 2004 The Society of Thoracic Surgeons

Invited commentary

Marc de Perrot, MD, MSc

Division of Thoracic Surgery, Toronto General Hospital200 Elizabeth StEN 10-224Toronto, Ontario, Canada M5G 2C4

marcdeperrot@hotmail.com

The first 20% of the full text of this article appears below.

Since the early 1970s, several studies have shown that high carcinoembryonic antigen (CEA) levels were a potential marker of poor prognosis in nonsmall cell lung cancer (NSCLC). Abnormally elevated CEA levels were reported in 30% to 70% of patients with NSCLC and were most frequently observed in patients with adenocarcinoma and advanced stage carcinoma. Despite its potential value, CEA was often falsely elevated in smokers and in patients with restrictive or obstructive pulmonary disease. Consequently, the stage of disease and performance status of the patients remained better predictors of survival than CEA, and in 1997, The American Thoracic Society and the European Respiratory Society did not recommend the routine measurement of CEA for patients with NSCLC, because it did not influence the management of these patients.

However, the past decade has been associated with significant changes in the mode of presentation and treatment of . . . [Full Text of this Article]


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Effect of histologic type and smoking status on interpretation of serum carcinoembryonic antigen value in non–small cell lung carcinoma
Morihito Okada, Wataru Nishio, Toshihiko Sakamoto, Kazuya Uchino, Tsuyoshi Yuki, Akio Nakagawa, and Noriaki Tsubota
Ann. Thorac. Surg. 2004 78: 1004-1009. [Abstract] [Full Text] [PDF]





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