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Ann Thorac Surg 2004;78:52-53
© 2004 The Society of Thoracic Surgeons

Invited commentary

Duke University Medical Center, Box 3094, Durham, NC 27710, USA

e-mail: h.grocott@duke.edu

The first 20% of the full text of this article appears below.

In this study by Fazio and colleagues, an important mystery in the field of peripheral marker detection of cardiac surgery-associated neurologic injury is answered. In an ideal world, the use of serum markers would provide an attractive means to diagnose brain injury in a setting where the clinical diagnosis is frequently hampered by the residual effects of anesthesia and imaging diagnostic techniques that either lack specificity and sensitivity or present logistical problems.

Indeed, a great deal of work has been published regarding the relationship of S100ß to neurologic injury in this setting. S100ß was once thought to be an ideal marker of cardiac surgery-associated neurologic injury because its glial cell origin made it brain . . . [Full Text of this Article]

This article has been cited by other articles:

				D.C. Whitaker, A.J.E. Green, J. Stygall, M.J.G. Harrison, and S.P. Newman Evaluation of an alternative S100b assay for use in cardiac surgery: relationship with microemboli and neuropsychological outcome Perfusion, July 1, 2007; 22(4): 267 - 272. [Abstract] [PDF]