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Ann Thorac Surg 2004;77:1133-1134
© 2004 The Society of Thoracic Surgeons

Correspondence

Immunosuppression and xenotransplantation of cells for cardiac repair: Reply

Yong-Fu Xiao, MD, PhD, Jiang-Yong Min, MD, James P. Morgan, MD, PhD

Cardiovascular Division, Beth Israel Deaconess Medical Center Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA

e-mail: yxiao@bidmc.harvard.edu

The first 20% of the full text of this article appears below.

To the Editor:


Dr Law discloses that he has a financial relationship with Cell Therapy, Inc.

 

We appreciate the comment of Haider and co-workers. We fully agree that the underlying mechanism of the survival of xenografted cells needs to be delineated. It has been shown that immunosuppression is required for the survival of xenotransplanted somatic cells in myocardium and that the chances of surviving are related to the degree of their differentiation [1]. The success of xenografts of adult stem cells in the heart without immunosuppression . . . [Full Text of this Article]






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