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Ann Thorac Surg 2004;77:382
© 2004 The Society of Thoracic Surgeons
a Department of Genetics, Harvard Medical School, 200 Longwood Ave, Boston, MA 02115, USA
b Department of Surgery, Division of Thoracic and Cardiovascular Surgery, Eberhard-Karls-Universität, Tübingen, Germany
e-mail: jschmitt@genetics.med.harvard.edu
| The first 20% of the full text of this article appears below. |
To the Editor:
Two modes of morphological change have been proposed to describe cell death, from apoptosis to necrosis and from oncosis to necrosis [1]. Whereas apoptosis is associated with nuclear changes such as chromatin condensation and DNA (deoxyribonucleic acid) fragmentation and with the formation of apoptotic bodies, characteristic features of oncosis are disruption of the plasma membrane and cell swelling [1].
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