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Ann Thorac Surg 2004;77:382
© 2004 The Society of Thoracic Surgeons

Correspondence

Oncosis rather than apoptosis?

Friedhelm Sayk, MDa

a Institute of Pathology, University of Luebeck, Luebeck, Germany

Claus Bartels, MDb

b Klinik für Herzchirurgie, Universitaetsklinikum Luebeck, Ratzeburger Allee 160, Luebeck D-23538, Germany

e-mail: bartels@medinf.mu-luebeck.de

The first 20% of the full text of this article appears below.

To the Editor:

We write with reference to the interesting and impressively well designed study of Schmitt and co-workers [1] concerning the mode of cardiomyocyte death in the context of cardioplegic arrest and reperfusion. Damage to single cardiomyocytes was investigated by electron microscopy, TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP-biotin end labeling of fragmented DNA [deoxyribonucleic acid]), and quantification of cytochrome c and citrate synthase release and was interpreted as apoptosis. However, some questions concerning this interpretation should be . . . [Full Text of this Article]






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