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Ann Thorac Surg 2003;76:827
© 2003 The Society of Thoracic Surgeons

Invited commentary

Larry W. Stephenson, MDa

a Division of Cardiothoracic Surgery, Wayne State University School of Medicine, Harper Professional Building, Suite 2102, 3990 John R Street, Detroit, MI 48201, USA

e-mail: lstephen@dmc.org

The first 20% of the full text of this article appears below.

Since Alain Carpentier and Juan Carlos Chachques introduced clinical cardiomyoplasty in 1985, an estimated 1000 of these procedures have been done worldwide. In the phase II clinical trials conducted in the United States under the auspices of the FDA, about 80%–85% of hospital survivors showed improvement in their signs and symptoms for heart failure from several months up to a year, and sometimes much longer.

The phase III randomized clinical trial, again under the auspices . . . [Full Text of this Article]







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