ATS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Gary L. Grunkemeier
John R. Handy, Jr
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Grunkemeier, G. L.
Right arrow Articles by Handy, J. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Grunkemeier, G. L.
Right arrow Articles by Handy, J. R., Jr
Related Collections
Right arrow Professional affairs

Ann Thorac Surg 2002;74:301-305
© 2002 The Society of Thoracic Surgeons

The statistician’s page

Propensity score analysis of stroke after off-pump coronary artery bypass grafting

Gary L. Grunkemeier, PhD*a, Nicola Payne, MPhiLa, Ruyun Jin, MDa, John R. Handy, Jr, MDa

a Providence Health System, Portland, Oregon, USA

* Address reprint requests to Dr Grunkemeier, 9155 SW Barnes Rd, #33, Portland, OR 97225 USA
e-mail: ggrunkemeier@providence.org

The first 300 words of the full text of this article appear below.

The article by Stamou and colleagues [1] found that the stroke rate after coronary artery bypass grafting (CABG) was lower for off-pump CABG than for conventional, on-pump CABG. Postoperative stroke occurred in 2.5% of on-pump patients and only 1.2% of off-pump CABG patients, for an (unadjusted) odds ratio (OR) of 2.1 for on-pump versus off-pump CABG (see Appendix for definition of OR). Because the two patient groups were not similar with respect to potential risk factors for stroke, they used a logistic regression, which produced an adjusted OR of 1.6. As an adjunctive analysis, they computed a propensity score and used it to find on-pump matches for 72% of the off-pump CABG patients. For these matched subsets the OR for postoperative stroke was 1.8.

This expository article briefly describes propensity scores and demonstrates another way of using them to compare treatments. We apply this method to another data set, and in the process corroborate the findings of Stamou and colleagues.

Propensity score: the concept

Propensity score analysis is about 20 years old, but has only recently begun to be used to any extent in medical research (Fig 1). One of the originators of this method recently wrote an overview article for physicians [2], and another recent review by Eugene Blackstone [3] provides a thorough discussion of this method.


Figure Removed (Available Only in the Full Text)
View larger version (15K):
[in this window]
[in a new window]
  		Fig 1. The number of papers from a Medline search using the text string "propensity score" according to the year of publication. This term has had a recent increase, although it is still not widely used.

 
Randomized studies are considered the highest level of evidence for comparing a treatment with a control. The essential feature of such studies is that some random mechanism controls treatment assignment, therefore each patient has the same probability of receiving the treatment, thus protecting against a biased comparison due to patient . . . [Full Text of this Article]




This article has been cited by other articles:


Home page
 Nicotine Tob ResHome page
K.-L. K. Sakuma, P. Sun, J. B. Unger, and C. A. Johnson
Evaluating Depressive Symptom Interactions on Adolescent Smoking Prevention Program Mediators: A Mediated Moderation Analysis
Nicotine Tob Res, November 1, 2010; 12(11): 1099 - 1107.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
A. Ali, A. Patel, Z. A. Ali, Y. Abu-Omar, D. Freed, A. Y. Sheikh, T. Athanasiou, and J. Pepper
Stentless aortic valve replacement in patients with bicuspid aortic valve disease: clinical outcome and aortic diameter changes during follow-up
Eur J Cardiothorac Surg, August 1, 2010; 38(2): 134 - 140.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
A. Ali, Y. Abu-Omar, A. Patel, A. Y. Sheikh, Z. Ali, A. Saeed, A. Akhtar, T. Athanasiou, and J. Pepper
Propensity analysis of survival after subcoronary or root replacement techniques for homograft aortic valve replacement.
J. Thorac. Cardiovasc. Surg., February 1, 2009; 137(2): 334 - 341.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
R. J. Moraca, M. R. Moon, J. S. Lawton, T. J. Guthrie, K. A. Aubuchon, N. Moazami, M. K. Pasque, and R. J. Damiano Jr
Outcomes of Tricuspid Valve Repair and Replacement: A Propensity Analysis
Ann. Thorac. Surg., January 1, 2009; 87(1): 83 - 89.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
B. F. Meyers, P. K. Sultan, T. J. Guthrie, S. S. Lefrak, G. E. Davis, G. A. Patterson, J. D. Cooper, and R. D. Yusen
Outcomes After Unilateral Lung Volume Reduction
Ann. Thorac. Surg., July 1, 2008; 86(1): 204 - 212.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
A. Ali, Y. Abu-Omar, A. Patel, Z. Ali, A. Y. Sheikh, A. Akhtar, A. Pavlovic, P. Theodorou, T. Athanasiou, and J. Pepper
Valve failure following homograft aortic valve replacement: does implantation technique have an effect?
Eur. Heart J., June 1, 2008; 29(11): 1454 - 1462.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
P. C. Austin
Propensity-score matching in the cardiovascular surgery literature from 2004 to 2006: a systematic review and suggestions for improvement.
J. Thorac. Cardiovasc. Surg., November 1, 2007; 134(5): 1128 - 1135.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Mishra, R. Malhotra, A. Karlekar, Y. Mishra, and N. Trehan
Propensity Case-Matched Analysis of Off-Pump Versus On-Pump Coronary Artery Bypass Grafting in Patients With Atheromatous Aorta
Ann. Thorac. Surg., August 1, 2006; 82(2): 608 - 614.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
A. J. Rastan, J. I. Eckenstein, B. Hentschel, A. K. Funkat, J. F. Gummert, N. Doll, T. Walther, V. Falk, and F. W. Mohr
Emergency Coronary Artery Bypass Graft Surgery for Acute Coronary Syndrome: Beating Heart Versus Conventional Cardioplegic Cardiac Arrest Strategies
Circulation, July 4, 2006; 114(1_suppl): I-477 - I-485.
[Abstract] [Full Text] [PDF]

Home page
 SEMIN CARDIOTHORAC VASC ANESTHHome page
G. N. Djaiani
Aortic arch atheroma: stroke reduction in cardiac surgical patients.
Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2006; 10(2): 143 - 157.
[Abstract] [PDF]

Home page
 CirculationHome page
E. I. Kapetanakis, D. A. Medlam, K. R. Petro, E. Haile, P. C. Hill, M. K.C. Dullum, A. S. Bafi, S. W. Boyce, and P. J. Corso
Effect of Clopidogrel Premedication in Off-Pump Cardiac Surgery: Are We Forfeiting the Benefits of Reduced Hemorrhagic Sequelae?
Circulation, April 4, 2006; 113(13): 1667 - 1674.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
S. C. Stamou, P. C. Hill, E. Haile, S. Prince, M. J. Mack, and P. J. Corso
Clinical outcomes of nonelective coronary revascularization with and without cardiopulmonary bypass
J. Thorac. Cardiovasc. Surg., January 1, 2006; 131(1): 28 - 33.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
D. N. Wijeysundera, W. S. Beattie, G. Djaiani, V. Rao, M. A. Borger, K. Karkouti, and R. J. Cusimano
Off-Pump Coronary Artery Surgery for Reducing Mortality and Morbidity: Meta-Analysis of Randomized and Observational Studies
J. Am. Coll. Cardiol., September 6, 2005; 46(5): 872 - 882.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. S. Lawton, H. B. Barner, M. S. Bailey, T. J. Guthrie, N. Moazami, M. K. Pasque, M. R. Moon, and R. J. Damiano Jr
Radial Artery Grafts in Women: Utilization and Results
Ann. Thorac. Surg., August 1, 2005; 80(2): 559 - 563.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
A. Weerasinghe, T. Athanasiou, S. Al-Ruzzeh, R. Casula, P. P. Tekkis, M. Amrani, P. Punjabi, K. Taylor, R. Stanbridge, and B. Glenville
Functional Renal Outcome in On-Pump and Off-Pump Coronary Revascularization: A Propensity-Based Analysis
Ann. Thorac. Surg., May 1, 2005; 79(5): 1577 - 1583.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
E. I. Kapetanakis, D. A. Medlam, S. W. Boyce, E. Haile, P. C. Hill, M. K.C. Dullum, A. S. Bafi, K. R. Petro, and P. J. Corso
Clopidogrel administration prior to coronary artery bypass grafting surgery: the cardiologist's panacea or the surgeon's headache?
Eur. Heart J., March 2, 2005; 26(6): 576 - 583.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
T. L. Frankel, S. C. Stamou, R. C. Lowery, E. I. Kapetanakis, P. C. Hill, E. Haile, and P. J. Corso
Risk factors for hemorrhage-related reexploration and blood transfusion after conventional versus coronary revascularization without cardiopulmonary bypass
Eur J Cardiothorac Surg, March 1, 2005; 27(3): 494 - 500.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. I. Kapetanakis, S. C. Stamou, M. K.C. Dullum, P. C. Hill, E. Haile, S. W. Boyce, A. S. Bafi, K. R. Petro, and P. J. Corso
The Impact of Aortic Manipulation on Neurologic Outcomes After Coronary Artery Bypass Surgery: A Risk-Adjusted Study
Ann. Thorac. Surg., November 1, 2004; 78(5): 1564 - 1571.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
D. M. Shahian, E. H. Blackstone, F. H. Edwards, F. L. Grover, G. L. Grunkemeier, D. C. Naftel, S. A.M. Nashef, W. C. Nugent, and E. D. Peterson
Cardiac Surgery Risk Models: A Position Article
Ann. Thorac. Surg., November 1, 2004; 78(5): 1868 - 1877.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
T. Athanasiou, O. Aziz, O. Mangoush, S. Al-Ruzzeh, S. Nair, V. Malinovski, R. Casula, and B. Glenville
Does off-pump coronary artery bypass reduce the incidence of post-operative atrial fibrillation? A question revisited
Eur J Cardiothorac Surg, October 1, 2004; 26(4): 701 - 710.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
M. J. Mack, P. Brown, F. Houser, M. Katz, A. Kugelmass, A. Simon, S. Battaglia, L. Tarkington, S. Culler, and E. Becker
On-Pump Versus Off-Pump Coronary Artery Bypass Surgery in a Matched Sample of Women: A Comparison of Outcomes
Circulation, September 14, 2004; 110(11_suppl_1): II-1 - II-6.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
S. C. Stamou, K. A. Jablonski, J. M. Garcia, S. W. Boyce, A. S. Bafi, and P. J. Corso
Operative mortality after conventional versus coronary revascularization without cardiopulmonary bypass
Eur J Cardiothorac Surg, September 1, 2004; 26(3): 549 - 553.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
P. Sergeant, P. Wouters, B. Meyns, C. Bert, J. Van Hemelrijck, C. Bogaerts, G. Sergeant, and K. Slabbaert
OPCAB versus early mortality and morbidity: an issue between clinical relevance and statistical significance
Eur J Cardiothorac Surg, May 1, 2004; 25(5): 779 - 785.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. S. Coselli, S. A. LeMaire, L. D. Conklin, and G. J. Adams
Left heart bypass during descending thoracic aortic aneurysm repair does not reduce the incidence of paraplegia
Ann. Thorac. Surg., April 1, 2004; 77(4): 1298 - 1303.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. Sharony, E. A. Grossi, P. C. Saunders, A. C. Galloway, R. Applebaum, G. H. Ribakove, A. T. Culliford, M. Kanchuger, I. Kronzon, and S. B. Colvin
Propensity case-matched analysis of off-pump coronary artery bypass grafting in patients with atheromatous aortic disease
J. Thorac. Cardiovasc. Surg., February 1, 2004; 127(2): 406 - 413.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
S. Al-Ruzzeh, T. Athanasiou, S. George, B. E. Glenville, A. C. DeSouza, J. R. Pepper, and M. Amrani
Is the use of cardiopulmonary bypass for multivessel coronary artery bypass surgery an independent predictor of operative mortality in patients with ischemic left ventricular dysfunction?
Ann. Thorac. Surg., August 1, 2003; 76(2): 444 - 451.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
V. A. Ferraris and S. P. Ferraris
Assessing the medical literature: let the buyer beware
Ann. Thorac. Surg., July 1, 2003; 76(1): 4 - 11.
[Abstract] [Full Text] [PDF]

Home page
 Eur J Cardiothorac SurgHome page
R. G. Fuster, J. A. M. Argudo, O. G. Albarova, F. H. Sos, S. C. Lopez, M. J. D. Sorli, M. B. Codoner, and J. A. B. Minano
Left ventricular mass index in aortic valve surgery: a new index for early valve replacement?
Eur J Cardiothorac Surg, May 1, 2003; 23(5): 696 - 702.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2002 by The Society of Thoracic Surgeons.