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Ann Thorac Surg 2002;73:S374
© 2002 The Society of Thoracic Surgeons

SUPPLEMENT: OUTCOMES 2001: SCIENTIFIC ABSTRACTS

Full dose aprotinin administration is associated with a significant decrease in perioperative stroke in patients undergoing elective cardiac surgery: a meta-analysis

John M. Murkin*, Jennifer Maurer#, Steve Niemcryk#

* Department of Anesthesia, University Campus LHSC, University of Western Ontario, London, Ontario, Canada
# Bayer Inc, New Haven, Conn, USA

Full dose aprotinin administration has been associated with a significant decrease in perioperative stroke in patients undergoing coronary artery bypass (CABG) surgery. To further assess this observation a meta-analysis of 7 placebo controlled, randomized, double-blind studies of CABG patients receiving full dose aprotinin or placebo was undertaken. [1–7] The rationale for . . . [Full Text of this Article]




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