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Ann Thorac Surg 2002;73:S368
© 2002 The Society of Thoracic Surgeons
a Departments of Anesthesiology and Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
Introduction. Neurobehavioral deficits are common after cardiopulmonary bypass, but magnetic resonance imaging (MRI) seldom reveals significant abnormalities. We would be better able to evaluate new neuroprotective interventions if a sensitive quantifiable measure of acute brain injury were available. Diffusion weighted imaging (DWI) is purported to be sensitive to acute brain injury, and several clinical trials are under way using DWI to determine if off-pump coronary artery bypass grafting causes less brain injury than traditional on-pump procedures. In an effort to empirically determine
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