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Ann Thorac Surg 2001;72:1938-1939
© 2001 The Society of Thoracic Surgeons

Invited commentary

Victor G. Davila-Roman, MDa, Charles W. Hogue, Jr, MDb

a Cardiovascular Imaging and Clinical Research Core Laboratory, Cardiovascular Division, Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave, Box 8086, St. Louis, MO 63110, USA
b Department of Anesthesiology, Washington University School of Medicine, 660 South Euclid Ave, Box 8086, St. Louis, MO 63110, USA

e-mail: vdavila@im.wustl.edu

Stroke is the third leading cause of death in the United States and is also a significant cause of morbidity and mortality for patients undergoing cardiac surgery [1]. For these patients, potential causes of postoperative stroke are many, and include hemodynamic alterations (ie, hypoperfusion), cerebral embolization (ie, atherosclerotic plaque, platelets, air, fat), and in-situ thrombosis or vasospasm due to alterations in procoagulant and inflammatory mediators activated during surgery. The majority (more than 75%) of perioperative strokes are delayed (ie, they occur after an initial, uneventful neurological recovery from surgery) [2]. Strategies to . . . [Full Text of this Article]


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Safety and efficacy of intraarterial thrombolysis for perioperative stroke after cardiac operation
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Ann. Thorac. Surg. 2001 72: 1933-1938. [Abstract] [Full Text] [PDF]





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