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Ann Thorac Surg 2001;72:666-667
© 2001 The Society of Thoracic Surgeons

Correspondence

S100 protein: its use as a marker of cerebral damage in cardiac operations

Natasha E. Khan, MRCSa, Anthony C. De Souza, FRCSa, John R. Pepper, FRCSa

a Department of Cardiothoracic Surgery, Royal Brompton and Harefield NHS Trust, Sydney St, London, England SW3 6NP, United Kingdom

e-mail: n.khan@rbh.nthames.nhs.uk

To the Editor

We read with interest the paper by Wandschneider and colleagues [1] on the reduced S100ß release in off-pump operations and congratulate them on their commitment to a randomized design. However, in light of recent other publications, the design of their project may not be satisfactory to draw conclusions on the suitability of S100ß as a marker of cerebral damage during bypass operations [2, 3]. It is becoming clear that during operations, levels of S100ß in pericardial and operative field blood are dramatically high, and these high levels are . . . [Full Text of this Article]






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Copyright © 2001 by The Society of Thoracic Surgeons.