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Ann Thorac Surg 2001;71:2085
© 2001 The Society of Thoracic Surgeons

Correspondence

S100 release as an indicator of cerebral damage

Donald Whitaker, FRCS(Ed)a

a The University College London Hospitals, Holmes Sellors Cardiothoracic Unit, The Middlesex Hospital, London, England, United Kingdom

e-mail: rmhkdcw@ucl.ac.uk

To the Editor

The recent suggestion by Wandschneider and colleagues [1] that avoiding cardiopulmonary bypass reduces perioperative cerebral injury remains an interesting hypothesis that has yet to be adequately tested. The hypothesis does not, however, seem to be supported by data from their study. For several reasons, serum S100ß is a controversial marker of cerebral injury during cardiac operation. These are not addressed in the article. First, although widely used, the Sangtec assay remains unvalidated by published data [2]. There are . . . [Full Text of this Article]


Related Article

S100 release as an indicator of cerebral damage: Reply
Wolfgang Wandschneider
Ann. Thorac. Surg. 2001 71: 2085-2086. [Extract] [Full Text] [PDF]



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