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Ann Thorac Surg 2001;71:1756
© 2001 The Society of Thoracic Surgeons
a Department of Cardiothoracic Surgery, University of Texas Medical Branch, 301 University Blvd, Route 0528, Galveston, TX 77555-0528, USA
(Email: slick@utmb.edu).
| The first 20% of the full text of this article appears below. |
To the Editor
Given Dr Clarks premises, Occams (therapeutic) razor favors pentoxifylline. The notion that a single injection of a drug—and one so common and safe as pentoxifylline (better known in its oral form as a rheologic "lubricant" for red blood cells in claudicators)—will ameliorate lung injury is enticing.
However, upon revisiting Dr Clarks groups papers, controlled reperfusion did not get its fair due. In their model of controlled reperfusion [1],
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