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Ann Thorac Surg 2001;71:954-955
© 2001 The Society of Thoracic Surgeons

Invited commentary

Stephen R. Hazelrigg, MDa

a Division of Cardiothoracic Surgery, Southern Illinois University, School of Medicine, 800 N Rutledge, Room D314, Springfield, IL 62781, USA

e-mail: shazelrigg@siumed.edu

This article by Dr Liu and colleagues addresses a very interesting area of study. Adhesion molecules are cell surface glycoproteins which anchor cells together. There are four classes of adhesion molecules of which the cadherins are considered the most important. Studies on a variety of carcinomas have suggested that decreased expression of these cadherin molecules correlates with an increased rate of metastasis and decreased survival. The postulate . . . [Full Text of this Article]






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