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Ann Thorac Surg 2000;70:405-406
© 2000 The Society of Thoracic Surgeons

Invited commentary

Invited commentary

David H. Harpole, Jr, MD

Division of Thoracic Surgery, Duke University Medical Center, DUMC-3617, Durham, NC 27710, USA,

e-mail: harpo002@mc.duke.edu

Invited commentary

Doctor Arinaga and colleagues provide an elegant basic science translational research study. Much has been learned through molecular biology about carcinogenesis and pathways of resistance to chemotherapy and subsequent apoptotic cellular death by lung tumors over the last ten years. Interest has centered around methods with which the tumors preserve and elongate the telomere which cap each arm of the eukaryotic chromosomes. Dr Arinaga’s team, using RT-PCR . . . [Full Text of this Article]


Related Article

Expression of human telomerase subunit genes in primary lung cancer and its clinical significance
Mitsuyuki Arinaga, Shigeki Shimizu, Kunihiko Gotoh, Nobuhiro Haruki, Takao Takahashi, Takashi Takahashi, and Tetsuya Mitsudomi
Ann. Thorac. Surg. 2000 70: 401-405. [Abstract] [Full Text] [PDF]





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