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Ann Thorac Surg 1996;61:1043-1044
© 1996 The Society of Thoracic Surgeons
Department of Cardiovascular Surgery, Tenri Hospital, 200Mishima, Tenri, Nara 632 Japan
| The first 20% of the full text of this article appears below. |
To the Editor:
In the August 1995 issue of The Annals, Boeckxstanens and Flameng [1] raise a valid question about retrograde cerebral perfusion (RCP), which does not perfuse the brain in an experiment using nonhuman primates. They described that their experimental setting was designed to be as close as possible to the clinical situation to obtain the answer. There was, however, a major modification of the method of RCP that differed from our clinical report. In their experiment, inferior caval blood was drained and the aorta was not opened during RCP. Consequently, the pressure of the inferior vena cava and right atrium must be lower than jugular vein pressure, nearly 0 mm Hg or less. On the other hand, the pressure in the brain system can be kept high, as Dr Bradley S. Allen pointed out in his discussion. This might promote massive shunt of the oxygenated blood from the internal jugular vein to the venous system of the body. Retrograde cerebral perfusion blood escaped to the area of lower pressure instead of the brain and the opened aorta. Therefore, Boeckxstanens and Flameng
Department of Cardiac Surgery, Katholieke Universiteit Leuven, Herestraat 49, B-3000 Leuven, Belgium
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