HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Yung-Chie Lee Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Hsieh, M.-S. Articles by Lee, Y.-C. Search for Related Content PubMed PubMed Citation Articles by Hsieh, M.-S. Articles by Lee, Y.-C. Related Collections Lung - other

---

Case Reports

Pulmonary Metastatic Giant Cell Tumors Presenting as Totally Hyalinized and Ossified Nodules

Min-Shu Hsieh, MD^a, Chen-Tu Wu, MD^a, Mong-Wei Lin, MD^b, Yih-Leong Chang, MD^a,_*, Yung-Chie Lee, MD, PhD^c,

^a Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
^b Department of Surgery, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan
^c Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan

Accepted for publication October 24, 2011.

^_* Address correspondence to Dr Chang, Department of Pathology, National Taiwan University Hospital, 7 Chung San South Rd, 10002, Taipei, Taiwan (Email: ntuhylc{at}gmail.com).

We report a case of giant cell tumor of the left distal femur with simultaneous bilateral pulmonary metastases. Pathologic examination of the left lung nodule showed a metastatic giant cell tumor with a noncontinuous ossified rim, and the right lung nodules were totally hyalinized or ossified without residual giant cell tumor components. Hyalinization was a consistent finding in both the primary bone lesion and the pulmonary metastases. Because the patient did not receive chemotherapy or radiotherapy before her surgical procedure, we believe that these changes represent spontaneous tumor regression.