HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Personal Folders Download to citation manager Author home page(s): Sander Bramer Jos G. Maessen Eric Berreklouw Permission Requests Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Bramer, S. Articles by Berreklouw, E. Search for Related Content PubMed PubMed Citation Articles by Bramer, S. Articles by Berreklouw, E. Related Collections Electrophysiology - arrhythmias Valve disease

---

Original Articles: Adult Cardiac

New-Onset Postoperative Atrial Fibrillation Predicts Late Mortality After Mitral Valve Surgery

^a Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands
^b Department of Education and Research, Catharina Hospital, Eindhoven, The Netherlands
^c Center of Research on Psychology in Somatic Diseases, Department of Medical Psychology, Tilburg University, Tilburg, The Netherlands
^d CoRPS, Department of Medical Psychology and Neuropsychology, Tilburg University, Tilburg, The Netherlands
^e Department of Cardiothoracic Surgery, Cardiovascular Research Institute Maastricht – CARIM, Maastricht University Medical Center – MUMC, Maastricht, The Netherlands

Accepted for publication June 22, 2011.

^_* Address correspondence to Dr Soliman Hamad, Department of Cardiothoracic Surgery, Catharina Hospital, Michelangelolaan 2, Postbus 1350, 5602 ZA Eindhoven, The Netherlands (Email: aasmsn{at}cze.nl).

Background: New-onset postoperative atrial fibrillation (POAF) is a common rhythm disturbance after mitral valve surgery. In this study we investigated the independent effect of POAF on early and late mortality after mitral valve surgery.

Methods: Data of patients who consecutively underwent mitral valve surgery with or without concomitant coronary or tricuspid valve surgery between January 2003 and June 2010 were prospectively collected. The study included 856 patients with preoperative sinus rhythm, and no history of atrial fibrillation. Logistic regression and Cox proportional hazard analyses were performed to investigate independent predictors of early and late mortality. Propensity score adjustment was performed to reduce the effect of confounders.

Results: The median follow-up was 3.1 years (range, 0 to 7.4 years). The POAF was documented in 361 patients (42%). Early mortality did not differ in patients with and without POAF (p = 0.93). Postoperative atrial fibrillation was not identified as predictor for early mortality. Late survival was worse in patients with POAF (log-rank, p < 0.001). Multivariate and propensity score adjusted Cox proportional hazard analyses demonstrated that POAF was an independent predictor for late mortality with hazard ratios of 2.09 and 1.61 (p = 0.001 and p = 0.033, respectively).

Conclusions: Postoperative atrial fibrillation is an independent predictor for late all-cause mortality after mitral valve surgery but not for early all-cause mortality.